Design and Synthesis of 99mTcN-Labeled Dextran-Mannose Derivatives for Sentinel Lymph Node Detection

• Main Authors: Alessandra Boschi (Author), Micòl Pasquali (Author), Claudio Trapella (Author), Alessandro Massi (Author), Petra Martini (Author), Adriano Duatti (Author), Remo Guerrini (Author), Vinicio Zanirato (Author), Anna Fantinati (Author), Erika Marzola (Author), Melchiore Giganti (Author), Licia Uccelli (Author)
• Format: Book
• Published: MDPI AG, 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: New approaches based on the receptor-targeted molecular interaction have been recently developed with the aim to investigate specific probes for sentinel lymph nodes. In particular, the mannose receptors expressed by lymph node macrophages became an attractive target and different multif...