Downregulation of tight junction protein zonula occludens-2 and urothelium damage in a cyclophosphamide-induced mouse model of cystitis

• Main Authors: Yung-Hsiang Chen (Author), Chao-Jung Chen (Author), Shih-Jing Wang (Author), Yu-Ning Lin (Author), Wen-Chi Chen (Author), Ming-Yen Tsai (Author), Huey-Yi Chen (Author)
• Format: Book
• Published: Elsevier, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: The cyclophosphamide (CYP)-induced model of cystitis in mice closely fits the symptoms of chronic bladder inflammation. Cystitis was recently found to be due to an altered gap junction protein in a rat model. Thus, this study was conducted to evaluate changes in protein expression and co...