Nanoemulsion-based delivery system for enhanced oral bioavailability and Caco-2 cell monolayers permeability of berberine hydrochloride

• Main Authors: Yong-Jiang Li (Author), Xiong-Bin Hu (Author), Xiu-Ling Lu (Author), De-Hua Liao (Author), Tian-Tian Tang (Author), Jun-Yong Wu (Author), Da-Xiong Xiang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Berberine hydrochloride (BBH) has a variety of pharmacological activities such as antitumor, antimicrobial, anti-inflammation, and reduce irritable bowel syndrome. However, poor stability and low oral bioavailability limited its usage. Herein, an oil-in-water nanoemulsion system of BBH was developed...