Risk of Hyponatremia after Tramadol/Acetaminophen Single-Pill Combination Therapy: A Real-World Study Based on the OMOP-CDM Database

• Main Authors: Yu Jeong Lee (Author), Jinmi Kim (Author), Youngmi Han (Author), Kyuhyun Hwang (Author), Byungkwan Choi (Author), Tae Ryom Oh (Author), Il Young Kim (Author), Harin Rhee (Author)
• Format: Book
• Published: Adis, Springer Healthcare, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background and Objective Tramadol has been reported to cause hyponatremia but the evidence is conflicting. The risk of hyponatremia resulting from combination oral tramadol/acetaminophen (TA) therapy is thus unknown. This study examined whether, compared with acetaminophen (AA), TA use is a...