Development of new non-viral systems for genetic modification of senescent cells

• Main Authors: Junquera López-Seijas (Author), Diego Miranda-Balbuena (Author), Alba Iglesias-Fente (Author), Marta Sacristán-Santos (Author), Natalia Carballo-Pedrares (Author), María C. Arufe (Author), Ana Rey-Rico (Author), Juan Fafián-Labora (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Senescence is a process characterized by a prolonged irreversible cell-cycle arrest. The accumulation of senescent cells in tissues is related to aging and to the development of age-related diseases. Recently, gene therapy has emerged as a powerful tool for treating age-associated diseases by the tr...