Endothelin-1 Induces Contraction via a Syk-Mediated p38 Mitogen-Activated Protein Kinase Pathway in Rat Aortic Smooth Muscle

• Main Authors: Hwan Myung Lee (Author), Kyung-Jong Won (Author), Junghwan Kim (Author), Hyo-Jun Park (Author), Hyo Jin Kim (Author), Hui Yul Roh (Author), So Hee Lee (Author), Chang-Kwon Lee (Author), Bokyung Kim (Author)
• Format: Book
• Published: Elsevier, 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although spleen tyrosine kinase (Syk) has crucial roles in various cells, its function on vascular smooth muscle contraction has not been determined. In the present study, we performed experiments to determine if Syk contributes to the endothelin-1 (ET-1)-mediated contraction in rat aortic smooth mu...