Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis

• मुख्य लेखकों: Yi Liu (लेखक), Yan-Yun Jing (लेखक), Chen-Ying Zeng (लेखक), Chen-Guang Li (लेखक), Li-Hui Xu (लेखक), Liang Yan (लेखक), Wen-Jing Bai (लेखक), Qing-Bing Zha (लेखक), Dong-Yun Ouyang (लेखक), Xian-Hui He (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2018-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The NLRP3 inflammasome plays a critical role in mediating the innate immune defense against pathogenic infections, but aberrant activation of NLRP3 inflammasome has been linked to a variety of inflammatory diseases. Thus targeting the NLRP3 inflammasome represents a promising therapeutic for the tre...