Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis

• Hoofdauteurs: Yi Liu (Auteur), Yan-Yun Jing (Auteur), Chen-Ying Zeng (Auteur), Chen-Guang Li (Auteur), Li-Hui Xu (Auteur), Liang Yan (Auteur), Wen-Jing Bai (Auteur), Qing-Bing Zha (Auteur), Dong-Yun Ouyang (Auteur), Xian-Hui He (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2018-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The NLRP3 inflammasome plays a critical role in mediating the innate immune defense against pathogenic infections, but aberrant activation of NLRP3 inflammasome has been linked to a variety of inflammatory diseases. Thus targeting the NLRP3 inflammasome represents a promising therapeutic for the tre...