Resveratrol inhibits arecoline-induced fibrotic properties of buccal mucosal fibroblasts via miR-200a activation

• Main Authors: Hui-Wen Yang (Author), Dennis Chun-Yu Ho (Author), Heng-Yi Liao (Author), Yi-Wen Liao (Author), Chih-Yuan Fang (Author), Min Yee Ng (Author), Cheng-Chia Yu (Author), Fu-Chen Lin (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Oral submucous fibrosis (OSF) is a precancerous lesion in the oral cavity, commonly results from the Areca nut chewing habit. Arecoline, the main component of Areca nut, is known to stimulate the activation of myofibroblasts, which can lead to abnormal collagen I deposition. Mean...