Surrogate endpoints: when to use and when not to use? A critical appraisal of current evidences

• Main Authors: PEDRAZZI Vinicius (Author), Fellipe Augusto Tocchini de FIGUEIREDO (Author), Larisse Eduardo ADAMI (Author), Flávia FURLANETO (Author), Daniela Bazan PALIOTO (Author), Michel Reis MESSORA (Author)
• Format: Book
• Published: Sociedade Brasileira de Pesquisa Odontológica, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Clinical research needs to formulate a question, which must be answered by obeying ethical precepts with well-defined inclusion/exclusion criteria and approval of the study on platforms of ethical appreciation and clinical trial records. In comparing the results or clinically relevant outco...