Immune tolerance promotion by LSEC-specific lentiviral vector-mediated expression of the transgene regulated by the stabilin-2 promoter

• Main Authors: Ester Borroni (Author), Chiara Borsotti (Author), Roberta A. Cirsmaru (Author), Vakhtang Kalandadze (Author), Rosella Famà (Author), Simone Merlin (Author), Brian Brown (Author), Antonia Follenzi (Author)
• 格式: 图书
• 出版: Elsevier, 2024-03-01T00:00:00Z.
• 主题: article
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Liver sinusoidal endothelial cells (LSECs) are specialized endocytic cells that clear the body from blood-borne pathogens and waste macromolecules through scavenger receptors (SRs). Among the various SRs expressed by LSECs is stabilin-2 (STAB2), a class H SR that binds to several ligands, among whic...