Promelaxin Microenemas Are Non-inferior to Oral Polyethylene Glycol for the Treatment of Functional Constipation in Young Children: A Randomized Clinical Trial

• Main Authors: Caterina Strisciuglio (Author), Vincenzo Coppola (Author), Marina Russo (Author), Carlo Tolone (Author), Gian Luigi Marseglia (Author), Alberto Verrotti (Author), Silvia Caimmi (Author), Claudia Caloisi (Author), Valeria D'Argenio (Author), Lucia Sacchetti (Author), Annamaria Staiano (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Polyethylene glycol (PEG) is recommended as first-line treatment of pediatric functional constipation. However, the oral route of administration is often poorly feasible in children mostly due to poor palatability. Promelaxin microenemas exert a topical evacuative action and may offer a...