Free heme and hemopexin in acute kidney injury after cardiopulmonary bypass and transient renal ischemia

• Main Authors: Robert Greite (Author), Sebastian Schott (Author), Li Wang (Author), Lukas Gohlke (Author), Kirill Kreimann (Author), Katja Derlin (Author), Marcel Gutberlet (Author), Martina Schmidbauer (Author), Andreas Leffler (Author), Igor Tudorache (Author), Jawad Salman (Author), Fabio Ius (Author), Ruslan Natanov (Author), Christine Fegbeutel (Author), Axel Haverich (Author), Ralf Lichtinghagen (Author), Anne M. Hüsing (Author), Sibylle vonVietinghoff (Author), Roland Schmitt (Author), Nelli Shushakova (Author), Song Rong (Author), Hermann Haller (Author), Kai M. Schmidt‐Ott (Author), Magnus Gram (Author), Vijith Vijayan (Author), Irina Scheffner (Author), Wilfried Gwinner (Author), Stephan Immenschuh (Author)
• Format: Book
• Published: Wiley, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Free heme is released from hemoproteins during hemolysis or ischemia reperfusion injury and can be pro‐inflammatory. Most studies on nephrotoxicity of hemolysis‐derived proteins focus on free hemoglobin (fHb) with heme as a prosthetic group. Measurement of heme in its free, non‐protein boun...