Redox Regulation of LAT Enhances T Cell-Mediated Inflammation

• Main Authors: Jaime James (Author), Ana Coelho (Author), Gonzalo Fernandez Lahore (Author), Clara M. Hernandez (Author), Florian Forster (Author), Bernard Malissen (Author), Rikard Holmdahl (Author)
• Format: Book
• Published: MDPI AG, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The positional cloning of single nucleotide polymorphisms (SNPs) of the neutrophil cytosolic factor 1 (<i>Ncf1</i>) gene, advocating that a low oxidative burst drives autoimmune disease, demands an understanding of the underlying molecular causes. A cellular target could be T cells, whic...