Cholinergic Machinery as Relevant Target in Acute Lymphoblastic T Leukemia

• Main Authors: Oxana Dobrovinskaya (Author), Georgina Valencia-Cruz (Author), Luis Castro-Sánchez (Author), Edgar Octavio Bonales-Alatorre (Author), Liliana Liñan-Rico (Author), Igor Pottosin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Various types of non-neuronal cells, including tumors, are able to produce acetylcholine (ACh), which acts as an autocrine/paracrine growth factor. T lymphocytes represent a key component of the non-neuronal cholinergic system. T cells-derived ACh is involved in a stimulation of their activation and...