Inhibitory Effect of KP-A038 on Osteoclastogenesis and Inflammatory Bone Loss Is Associated With Downregulation of Blimp1

• Main Authors: Hye Jung Ihn (Author), Taeho Lee (Author), Doohyun Lee (Author), Jong-Sup Bae (Author), Sang-Hyun Kim (Author), Il Ho Jang (Author), Yong Chul Bae (Author), Hong-In Shin (Author), Eui Kyun Park (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Excessive osteoclastic activity results in pathological bone resorptive diseases, such as osteoporosis, periodontitis, and rheumatoid arthritis. As imidazole-containing compounds possess extensive therapeutic potential for the management of diverse diseases, we synthesized a series of imidazole deri...