Engineering cannabidiol synergistic carbon monoxide nanocomplexes to enhance cancer therapy via excessive autophagy

• Egile Nagusiak: Chang Xiao (Egilea), Yue Sun (Egilea), Jialong Fan (Egilea), William Nguyen (Egilea), Simin Chen (Egilea), Ying Long (Egilea), Wei Chen (Egilea), Aiguo Zhu (Egilea), Bin Liu (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2023-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Although carbon monoxide (CO)-based treatments have demonstrated the high cancer efficacy by promoting mitochondrial damage and core-region penetrating ability, the efficiency was often compromised by protective autophagy (mitophagy). Herein, cannabidiol (CBD) is integrated into biomimetic carbon mo...