Genetic evidence for predisposition to acute leukemias due to a missense mutation (p.Ser518Arg) in ZAP70 kinase: a case-control study

• Main Authors: Khalil Khashei Varnamkhasti (Author), Samire Khashei Varnamkhasti (Author), Atefeh Shahrouzian (Author), Masoomeh Rahimzadeh (Author), Leila Naeimi (Author), Behrouz Naeimi (Author), Sirous Naeimi (Author)
• Format: Book
• Published: BMC, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The apparent lack of additional missense mutations data on mixed-phenotype leukemia is noteworthy. Single amino acid substitution by these non-synonymous single nucleotide variations can be related to many pathological conditions and may influence susceptibility to disease. This...