Structural diversity of Burkholderia pseudomallei lipopolysaccharides affects innate immune signaling.

• Päätekijät: Michael H Norris (Tekijä), Herbert P Schweizer (Tekijä), Apichai Tuanyok (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Public Library of Science (PLoS), 2017-04-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Burkholderia pseudomallei (Bp) causes the disease melioidosis. The main cause of mortality in this disease is septic shock triggered by the host responding to lipopolysaccharide (LPS) components of the Gram-negative outer membrane. Bp LPS is thought to be a weak inducer of the host immune system. LP...