Reliable Prediction of Caco-2 Permeability by Supervised Recursive Machine Learning Approaches

• Main Authors: Gabriela Falcón-Cano (Author), Christophe Molina (Author), Miguel Ángel Cabrera-Pérez (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2022-09-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

The heterogeneity of the Caco-2 cell line and differences in experimental protocols for permeability assessment using this cell-based method have resulted in the high variability of Caco-2 permeability measurements. These problems have limited the generation of large datasets to develop accurate and...