Oxidative low-density lipoprotein oxLDL induces pyroptosis in trophoblast cells HTR-8/Svneo by downregulating TET2

• Main Authors: Ting TAO (Author), Jing YAN (Author), Ziling LIAO (Author), Wenmao ZHANG (Author), Changqiong XU (Author), Ran LI (Author)
• Format: Book
• Published: KeAi Communications Co., Ltd., 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To investigate pyroptosis in the trophoblast cells HTR-8/Svneo induced by TET2 in oxidized low-density lipoprotein (oxLDL). Methods: HTR-8/Svneo cells were treated with vehicle (0 mg/L) and 50 mg/L oxLDL for 24 h. The effects of oxLDL on TET2 expression in HTR-8/Svneo cells were detected...