Functionalized methoxy quinoline derivatives: Experimental and in silico evaluation as new antiepileptic, anti-Alzheimer, antibacterial and antifungal drug candidates

• Main Authors: Bilge Çi̇ftci̇ (Author), Salih Ökten (Author), Ümit Muhammet Koçyi̇ği̇t (Author), Vildan Enisoğlu Atalay (Author), Mehmet Ataş (Author), Osman Çakmak (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The objective of this study was to assess the inhibitory effects of newly synthesized quinoline derivatives on human carbonic anhydrase I and II (hCA I and II), as well as acetylcholinesterase (AChE) enzymes, alongside their impact on various microorganisms. The synthesized compounds were assessed u...