The protective role of CD73 in periodontitis: preventing hyper-inflammatory fibroblasts and driving osteoclast energy metabolism

• Главные авторы: Erivan S. Ramos-Junior (Автор), Shantiece Dawson (Автор), Weston Ryan (Автор), Braden Clinebell (Автор), Rogelio Serrano-Lopez (Автор), Marsha Russell (Автор), Rylee Brumbaugh (Автор), Roger Zhong (Автор), Jussara Gonçalves Fernandes (Автор), Luciana M. Shaddox (Автор), Christopher W. Cutler (Автор), Ana Carolina Morandini (Автор)
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• Опубликовано: Frontiers Media S.A., 2023-12-01T00:00:00Z.
• Предметы: article
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IntroductionPeriodontitis is an immune-mediated inflammatory disease affecting almost half of the adult population and is the leading cause of tooth loss in the United States. The role of extracellular nucleotide signaling including nucleotide metabolizing enzyme CD73 adds an important layer of inte...