The protective role of CD73 in periodontitis: preventing hyper-inflammatory fibroblasts and driving osteoclast energy metabolism

• Main Authors: Erivan S. Ramos-Junior (Author), Shantiece Dawson (Author), Weston Ryan (Author), Braden Clinebell (Author), Rogelio Serrano-Lopez (Author), Marsha Russell (Author), Rylee Brumbaugh (Author), Roger Zhong (Author), Jussara Gonçalves Fernandes (Author), Luciana M. Shaddox (Author), Christopher W. Cutler (Author), Ana Carolina Morandini (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionPeriodontitis is an immune-mediated inflammatory disease affecting almost half of the adult population and is the leading cause of tooth loss in the United States. The role of extracellular nucleotide signaling including nucleotide metabolizing enzyme CD73 adds an important layer of inte...