Impact of mono- and di-β-galactose moieties in in vitro / in vivo anticancer efficacy of pyropheophorbide-carbohydrate conjugates by photodynamic therapy

• Main Authors: Mykhaylo Dukh (Author), Joseph Cacaccio (Author), Farukh A. Durrani (Author), Ishaan Kumar (Author), Ramona Watson (Author), Walter A. Tabaczynski (Author), Penny Joshi (Author), Joseph R. Missert (Author), Heinz Baumann (Author), Ravindra K. Pandey (Author)
• Format: Book
• Published: Elsevier, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To investigate the impact of mono- and di-β-galactose moieties in tumor uptake and photodynamic therapy (PDT) efficacy, HPPH [3-(1'-hexyloxy)ethyl-3-devinylpyropheophorobide-a], the meso pyropheophorbide-a [3-ethyl-3-devinyl-pyropheophorbide-a], and the corresponding 20-benzoic acid analogs wer...