In Vitro Cultivation of Limbal Epithelial Stem Cells on Surface-Modified Crosslinked Collagen Scaffolds

• Main Authors: Michel Haagdorens (Author), Vytautas Cėpla (Author), Eline Melsbach (Author), Laura Koivusalo (Author), Heli Skottman (Author), May Griffith (Author), Ramūnas Valiokas (Author), Nadia Zakaria (Author), Isabel Pintelon (Author), Marie-José Tassignon (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose. To investigate the efficacy of recombinant human collagen type I (RHC I) and collagen-like peptide (CLP) hydrogels as alternative carrier substrates for the cultivation of limbal epithelial stem cells (LESC) under xeno-free culture conditions. Methods. Human LESC were cultivated on seven di...