Bioassay-guided isolation of leishmanicidal cucurbitacins from Momordica charantia

• Main Authors: Maria Carolina Silva Marques (Author), Nídia Cristiane Yoshida (Author), Eduardo Caio Torres-Santos (Author), Fernanda Rodrigues Garcez (Author), Walmir Silva Garcez (Author)
• פורמט: ספר
• יצא לאור: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

IntroductionLeishmaniasis, a neglected tropical parasitic disease, is regarded as a major public health problem worldwide. The first-line drugs for leishmaniasis suffer from limitations related to toxicity and the development of resistance in certain parasitic strains. Therefore, the discovery of al...