Nanodrugs Detonate Lysosome Bombs

• Main Authors: Yuting Xiang (Author), Niansheng Li (Author), Min Liu (Author), Qiaohui Chen (Author), Xingyu Long (Author), Yuqi Yang (Author), Zuoxiu Xiao (Author), Jia Huang (Author), Xiaoyuan Wang (Author), Yunrong Yang (Author), Jinping Zhang (Author), Chong Liu (Author), Qiong Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cancer cell lysosomes contain various hydrolases and non-degraded substrates that are corrosive enough to destroy cancer cells. However, many traditional small molecule drugs targeting lysosomes have strong side effects because they cannot effectively differentiate between normal and cancer cells. M...