Therapeutic Opportunities of GPBAR1 in Cholestatic Diseases

• Main Authors: Fangling Zhang (Author), Xiaolin Xiao (Author), Yong Li (Author), Hefei Wu (Author), Xinyu Deng (Author), Yinxiao Jiang (Author), Wenwen Zhang (Author), Jian Wang (Author), Xiao Ma (Author), Yanling Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

GPBAR1, a transmembrane G protein-coupled receptor for bile acids, is widely expressed in multiple tissues in humans and rodents. In recent years, GPBAR1 has been thought to play an important role in bile homeostasis, metabolism and inflammation. This review specifically focuses on the function of G...