Quercetin Attenuates Quinocetone-Induced Cell Apoptosis In Vitro by Activating the P38/Nrf2/HO-1 Pathway and Inhibiting the ROS/Mitochondrial Apoptotic Pathway

• Main Authors: Chongshan Dai (Author), Qinzhi Zhang (Author), Linjie Shen (Author), Gaurav Sharma (Author), Haiyang Jiang (Author), Zhanhui Wang (Author), Jianzhong Shen (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Quinocetone (QCT), a member of the quinoxaline 1,4-di-<i>N</i>-oxides (QdNOs) family, can cause genotoxicity and hepatotoxicity, however, the precise molecular mechanisms of QCT are unclear. This present study investigated the protective effect of quercetin on QCT-induced cytotoxicity an...