T3 and glucose increase expression of phosphoenolpyruvate carboxykinase (PCK1) leading to increased β-cell proliferation

Objectives: Thyroid hormone (T3) and high glucose concentrations are critical components of β-cell maturation and function. In the present study, we asked whether T3 and glucose signaling pathways coordinately regulate transcription of genes important for β-cell function and proliferation. Methods:...

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Main Authors: Liora S. Katz (Author), Carmen Argmann (Author), Luca Lambertini (Author), Donald K. Scott (Author)
Format: Book
Published: Elsevier, 2022-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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