T3 and glucose increase expression of phosphoenolpyruvate carboxykinase (PCK1) leading to increased β-cell proliferation
Objectives: Thyroid hormone (T3) and high glucose concentrations are critical components of β-cell maturation and function. In the present study, we asked whether T3 and glucose signaling pathways coordinately regulate transcription of genes important for β-cell function and proliferation. Methods:...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
Elsevier,
2022-12-01T00:00:00Z.
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