Protection of Polyphenols against Glyco-Oxidative Stress: Involvement of Glyoxalase Pathway

• Main Authors: Laura Cianfruglia (Author), Camilla Morresi (Author), Tiziana Bacchetti (Author), Tatiana Armeni (Author), Gianna Ferretti (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic high glucose (HG) exposure increases methylglyoxal (MGO)-derived advanced glycation end-products (AGEs) and is involved in the onset of pathological conditions, such as diabetes, atherosclerosis and chronic-degenerative diseases. Under physiologic conditions the harmful effects of MGO are co...