Cdkn2a deficiency promotes adipose tissue browning

• Main Authors: Nabil Rabhi (Author), Sarah Anissa Hannou (Author), Xavier Gromada (Author), Elisabet Salas (Author), Xi Yao (Author), Frédérik Oger (Author), Charlène Carney (Author), Isabel C. Lopez-Mejia (Author), Emmanuelle Durand (Author), Iandry Rabearivelo (Author), Amélie Bonnefond (Author), Emilie Caron (Author), Lluis Fajas (Author), Christian Dani (Author), Philippe Froguel (Author), Jean-Sébastien Annicotte (Author)
• Format: Book
• Published: Elsevier, 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Genome-wide association studies have reported that DNA polymorphisms at the CDKN2A locus modulate fasting glucose in human and contribute to type 2 diabetes (T2D) risk. Yet the causal relationship between this gene and defective energy homeostasis remains elusive. Here we sought to under...