lncRNA PVT1 Promotes Tumorigenesis of Colorectal Cancer by Stabilizing miR-16-5p and Interacting with the VEGFA/VEGFR1/AKT Axis

• Main Authors: Hailu Wu (Author), Ming Wei (Author), Xinglu Jiang (Author), Jiacheng Tan (Author), Wei Xu (Author), Xiaobo Fan (Author), Rui Zhang (Author), Chenbo Ding (Author), Fengfeng Zhao (Author), Xiangyu Shao (Author), Zhigang Zhang (Author), Ruihua Shi (Author), Weijia Zhang (Author), Guoqiu Wu (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recently, the long noncoding RNA (lncRNA) plasmacytoma variant translocation 1 (PVT1) was reported to be involved in the pathogenesis of several cancers, including human colorectal cancer (CRC). However, the molecular basis for cancer initiation, development, and progression remains unclear. In this...