Dexamethasone prevents interleukin-1β-induced nuclear factor-κB activation by upregulating IκB-α synthesis, in lymphoblastic cells

• Asıl Yazarlar: M. Castro-caldas (Yazar), A. F. Mendes (Yazar), A. P. Carvalho (Yazar), C. B. Duarte (Yazar), M. C. Lopes (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Hindawi Limited, 2003-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Aims: Glucocorticoids (GCs) exert some of their anti-inflammatory actions by preventing the activation of the transcription factor nuclear factor (NF)-κB. The GC-dependent inhibition of NF-κB may occur at different levels, but the mechanisms involved are still incompletely understood. In this work,...