Health economic analysis of polygenic risk score use in primary prevention of coronary artery disease - A system dynamics model

• Päätekijät: Stephen T. Vernon (Tekijä), Stuart Brentnall (Tekijä), Danielle J Currie (Tekijä), Cindy Peng (Tekijä), Michael P. Gray (Tekijä), Giordano Botta (Tekijä), Deo Mujwara (Tekijä), Stephen J. Nicholls (Tekijä), Stuart M. Grieve (Tekijä), Julie Redfern (Tekijä), Clara Chow (Tekijä), Jean-Frederic Levesque (Tekijä), Peter J. Meikle (Tekijä), Garry Jennings (Tekijä), Zanfina Ademi (Tekijä), Andrew Wilson (Tekijä), Gemma A. Figtree (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2024-06-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Background: Primary prevention programs utilising traditional risk scores fail to identify all individuals who suffer acute cardiovascular events. We aimed to model the impact and cost effectiveness of incorporating a Polygenic risk scores (PRS) into the cardiovascular disease CVD primary prevention...