Fitter Mitochondria Are Associated With Radioresistance in Human Head and Neck SQD9 Cancer Cells

• Main Authors: Debora Grasso (Author), Hyllana C. D. Medeiros (Author), Luca X. Zampieri (Author), Vanesa Bol (Author), Pierre Danhier (Author), Marike W. van Gisbergen (Author), Caroline Bouzin (Author), Davide Brusa (Author), Vincent Grégoire (Author), Hubert Smeets (Author), Alphons P. M. Stassen (Author), Ludwig J. Dubois (Author), Philippe Lambin (Author), Marie Dutreix (Author), Pierre Sonveaux (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The clinical management of head and neck squamous cell carcinoma (HNSCC) commonly involves chemoradiotherapy, but recurrences often occur that are associated with radioresistance. Using human SQD9 laryngeal squamous cell carcinoma cancer cells as a model, we aimed to identify metabolic changes assoc...