Parasite-derived microRNAs in host serum as novel biomarkers of helminth infection.

• Main Authors: Anna M Hoy (Author), Rachel J Lundie (Author), Alasdair Ivens (Author), Juan F Quintana (Author), Norman Nausch (Author), Thorsten Forster (Author), Frances Jones (Author), Narcis B Kabatereine (Author), David W Dunne (Author), Francisca Mutapi (Author), Andrew S Macdonald (Author), Amy H Buck (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

MicroRNAs (miRNAs) are a class of short non-coding RNA that play important roles in disease processes in animals and are present in a highly stable cell-free form in body fluids. Here, we examine the capacity of host and parasite miRNAs to serve as tissue or serum biomarkers of Schistosoma mansoni i...