Conjugation of Penicillin-G with Silver(I) Ions Expands Its Antimicrobial Activity against Gram Negative Bacteria

• Main Authors: Ioannis Ketikidis (Author), Christina N. Banti (Author), Nikolaos Kourkoumelis (Author), Constantinos G. Tsiafoulis (Author), Christina Papachristodoulou (Author), Angelos G. Kalampounias (Author), Sotiris K. Hadjikakou (Author)
• Format: Book
• Published: MDPI AG, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Conjugation of penicillin G (<b>PenH</b>) with silver(I) ions forms a new CoMeD (conjugate of metal with a drug) with formula [Ag(pen)(CH₃OH)]₂ (<b>PenAg</b>). <b>PenAg</b> was characterized by a plethora of physical a...