Tamoxifen Inhibits Cardiac ATP-Sensitive and Acetylcholine-Activated K+ Currents in Part by Interfering With Phosphatidylinositol 4,5-Bisphosphate-Channel Interaction
Tamoxifen inhibits transmembrane currents of the Kir2.x inward rectifier potassium channels by interfering with the interaction of the channels with membrane phosphatidylinositol 4,5-bisphosphate (PIP2). We tested the hypothesis that Kir channels with low affinity for PIP2, like the adenosine tripho...
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Main Authors: | , , , , |
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Format: | Book |
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Elsevier,
2010-01-01T00:00:00Z.
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A1234.567 |
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