Tamoxifen Inhibits Cardiac ATP-Sensitive and Acetylcholine-Activated K+ Currents in Part by Interfering With Phosphatidylinositol 4,5-Bisphosphate-Channel Interaction

Tamoxifen inhibits transmembrane currents of the Kir2.x inward rectifier potassium channels by interfering with the interaction of the channels with membrane phosphatidylinositol 4,5-bisphosphate (PIP2). We tested the hypothesis that Kir channels with low affinity for PIP2, like the adenosine tripho...

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Main Authors: Daniela Ponce-Balbuena (Author), Eloy G. Moreno-Galindo (Author), Angélica López-Izquierdo (Author), Tania Ferrer (Author), José A. Sánchez-Chapula (Author)
Format: Book
Published: Elsevier, 2010-01-01T00:00:00Z.
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Call Number: A1234.567
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