Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle

• Main Authors: Robert S. Lee-Young (Author), Nolan J. Hoffman (Author), Kate T. Murphy (Author), Darren C. Henstridge (Author), Dorit Samocha-Bonet (Author), Andrew L. Siebel (Author), Peter Iliades (Author), Borivoj Zivanovic (Author), Yet H. Hong (Author), Timothy D. Colgan (Author), Michael J. Kraakman (Author), Clinton R. Bruce (Author), Paul Gregorevic (Author), Glenn K. McConell (Author), Gordon S. Lynch (Author), Grant R. Drummond (Author), Bronwyn A. Kingwell (Author), Jerry R. Greenfield (Author), Mark A. Febbraio (Author)
• Format: Book
• Published: Elsevier, 2016-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The development of skeletal muscle insulin resistance is an early physiological defect, yet the intracellular mechanisms accounting for this metabolic defect remained unresolved. Here, we have examined the role of glucose-6-phosphate dehydrogenase (G6PDH) activity in the pathogenesis of i...