Altered Gut Structure and Anti-Bacterial Defense in Adult Mice Treated with Antibiotics during Early Life

• Main Authors: Tnia Martins Garcia (Author), Manon van Roest (Author), Jacqueline L. M. Vermeulen (Author), Sander Meisner (Author), Jan Koster (Author), Manon E. Wildenberg (Author), Ruurd M. van Elburg (Author), Vanesa Muncan (Author), Ingrid B. Renes (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The association between prolonged antibiotic (AB) use in neonates and increased incidence of later life diseases is not yet fully understood. AB treatment in early life alters intestinal epithelial cell composition, functioning, and maturation, which could be the basis for later life health effects....