Novel pyrrolizines bearing 3,4,5-trimethoxyphenyl moiety: design, synthesis, molecular docking, and biological evaluation as potential multi-target cytotoxic agents

In the present study, two new series of pyrrolizines bearing 3,4,5-trimethoxyphenyl moiety were designed, synthesised, and evaluated for their cytotoxic activity. The benzamide derivatives 16a-e showed higher cytotoxicity than their corresponding Schiff bases 15a-e. Compounds 16a,b,d also inhibited...

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Bibliographic Details
Main Authors: Ahmed M. Shawky (Author), Nashwa A. Ibrahim (Author), Ashraf N. Abdalla (Author), Mohammed A. S. Abourehab (Author), Ahmed M. Gouda (Author)
Format: Book
Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
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Call Number: A1234.567
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