In vivo metabolic effects after acute activation of skeletal muscle Gs signaling

• Main Authors: Jaroslawna Meister (Author), Derek B.J. Bone (Author), Jonas R. Knudsen (Author), Luiz F. Barella (Author), Liu Liu (Author), Regina Lee (Author), Oksana Gavrilova (Author), Min Chen (Author), Lee S. Weinstein (Author), Maximilian Kleinert (Author), Thomas E. Jensen (Author), Jürgen Wess (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The goal of this study was to determine the glucometabolic effects of acute activation of Gs signaling in skeletal muscle (SKM) in vivo and its contribution to whole-body glucose homeostasis. Methods: To address this question, we studied mice that express a Gs-coupled designer G protein-c...