Role of acid-sensing ion channel 3 in sub-acute-phase inflammation

• Main Authors: Chen Chien-Ju (Author), Tu Pan-Hsien (Author), Yen Yi-Tin (Author), Lin Yi-Wen (Author), Hsieh Sung-Tsang (Author), Chen Chih-Cheng (Author)
• Format: Book
• Published: SAGE Publishing, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Inflammation-mediated hyperalgesia involves tissue acidosis and sensitization of nociceptors. Many studies have reported increased expression of acid-sensing ion channel 3 (ASIC3) in inflammation and enhanced ASIC3 channel activity w...