CGRP Is Critical for Hot Flushes in Ovariectomized Mice

• Main Authors: Daniel B. Wilhelms (Author), Hua Dock (Author), Haissa O. Brito (Author), Emma Pettersson (Author), Andrea Stojakovic (Author), Joanna Zajdel (Author), David Engblom (Author), Elvar Theodorsson (Author), Mats L. Hammar (Author), Anna-Clara E. Spetz Holm (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2019-01-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Hot flushes are common and troublesome symptoms of menopause. The neuropeptide calcitonin gene-related peptide (CGRP) is increased in plasma during hot flushes but it has not been clear if CGRP is causally involved in the mechanism underpinning the flushes. Here, we examined the effect of interventi...