Activation of Transient Receptor Potential Vanilloid-3 Channels in Keratinocytes Induces Pruritus in Humans

• Main Authors: Jin Cheol Kim (Author), Han Bi Kim (Author), Won-Sik Shim (Author), In Suk Kwak (Author), Bo Young Chung (Author), Seok Young Kang (Author), Chun Wook Park (Author), Hye One Kim (Author)
• Format: Book
• Published: Medical Journals Sweden, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Carvacrol, a natural transient receptor potential vanilloid-3 activator, has been reported to cause pruritus in mice. This study aimed to evaluate the effects of carvacrol and various antipruritic agents in humans. A stimulation test with carvacrol, β-alanine, and histamine was performed. After appl...