Activation of Transient Receptor Potential Vanilloid-3 Channels in Keratinocytes Induces Pruritus in Humans

• Principais autores: Jin Cheol Kim (Autor), Han Bi Kim (Autor), Won-Sik Shim (Autor), In Suk Kwak (Autor), Bo Young Chung (Autor), Seok Young Kang (Autor), Chun Wook Park (Autor), Hye One Kim (Autor)
• Formato: Livro
• Publicado em: Medical Journals Sweden, 2021-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Carvacrol, a natural transient receptor potential vanilloid-3 activator, has been reported to cause pruritus in mice. This study aimed to evaluate the effects of carvacrol and various antipruritic agents in humans. A stimulation test with carvacrol, β-alanine, and histamine was performed. After appl...