Role of neurosteroid allopregnanolone on age-related differences in exercise-induced hypoalgesia in rats

• Main Authors: Bun Aoyama (Author), Takashi Kawano (Author), Hideki Iwata (Author), Atsushi Nishigaki (Author), Daiki Yamanaka (Author), Hiroki Tateiwa (Author), Marie Shigematsu-Locatelli (Author), Satoru Eguchi (Author), Fabricio M. Locatelli (Author), Masataka Yokoyama (Author)
• Format: Book
• Published: Elsevier, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The beneficial effects of physical activity for pain are denominated exercise-induced hypoalgesia (EIH). Here, we examined the age-related change and potential role of the neurosteroid allopregnanolone (ALLO) on EIH in rats. Adult and aged rats were randomly divided into one of three groups; non-exe...