Transforming growth factor beta induces sensory neuronal hyperexcitability, and contributes to pancreatic pain and hyperalgesia in rats with chronic pancreatitis

• Main Authors: Zhu Yaohui (Author), Colak Tugba (Author), Shenoy Mohan (Author), Liu Liansheng (Author), Mehta Kshama (Author), Pai Reetesh (Author), Zou Bende (Author), Xie Xinmin (Author), Pasricha Pankaj J (Author)
• Format: Book
• Published: SAGE Publishing, 2012-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Transforming growth factor beta (TGFβ) is upregulated in chronic inflammation, where it plays a key role in wound healing and promoting fibrosis. However, little is known about the peripheral effects of TGFβ on nociception.</p>...