Reproductive and fetal toxicity studies of histamine H3 receptor antagonist DL76 used in mice to prevent maximal electroshock-induced seizure

• Main Authors: Salim M. Bastaki (Author), Yousef M. Abdulrazzaq (Author), Marwan Abdelrahim Zidan (Author), Mohamed Shafiullah (Author), Saif Ghdayer Alaryani (Author), Fatima Awad Alnuaimi (Author), Ernest Adeghate (Author), Sahar Mohsin (Author), Amal Akour (Author), Agata Siwek (Author), Dorota Łażewska (Author), Katarzyna Kieć-Kononowicz (Author), Bassem Sadek (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Brain histamine is considered an endogenous anticonvulsant and histamine H1 receptor. H1R antagonists have, in earlier studies, been found to induce convulsions. Moreover, research during the last two decades has provided more information concerning the anticonvulsant activities of his...