Expansion of parasite-specific CD4+ and CD8+ T cells expressing IL-10 superfamily cytokine members and their regulation in human lymphatic filariasis.

• मुख्य लेखकों: Rajamanickam Anuradha (लेखक), Parakkal Jovvian George (लेखक), Luke E Hanna (लेखक), Paul Kumaran (लेखक), Vedachalam Chandrasekaran (लेखक), Thomas B Nutman (लेखक), Subash Babu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2014-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Lymphatic filariasis (LF) is known to be associated with an increased production of IL-10. The role of the other IL-10 family members in the pathogenesis of infection and/or disease is not known.We examined the expression patterns of IL-10 family members--IL-19, IL-24 and IL-26 in LF. We demonstrate...